AdvanceBio Spin Columns from Agilent
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Agilent's AdvanceBio spin columns are designed for fast and simple sample preparation of proteins and oligonucleotides, making them ideal for desalting or buffer exchange. These gel-filtration-based spin columns and plates remove excess salts and small molecules, preserving the native structure of biomolecules in aqueous conditions, with suitable ionic strength and pH. This ensures your sample is ready for high-quality analysis while protecting LC columns and MS instruments from contamination and improving the accuracy of results.
Three formats are available for application flexibility: analytical and semi-preparative scale spin columns for individual samples, as well as 96-sample plates for high-throughput workflows.
- Analytical scale spin columns for up to 100 µL per sample
- Semi-preparative scale spin columns for up to 1 mL per sample
- Analytical scale 96-sample plates for up to 50 µL per sample
Features
- Ideal for desalting, buffer exchange, or removing reaction by-products in protein and oligonucleotide workflows
- Utilises cross-linked dextran particles for reliable sample processing across all formats
- Versatile formats - available in analytical scale columns, semi-preparative scale columns, and 96-sample plates for high-throughput workflows
- Fast sample preparation - process samples in just 10 to 15 minutes using a centrifuge
- Removes excess salts and small molecules, improving sample quality
- Protects instrumentation - reduces salt concentration and removes non-volatile buffers, preventing contamination and extending instrument uptime
- Improves peak shape and reduces clogs for better chromatography and mass spectrometry results
