Tosoh BioScience SkillPak HIC

SkillPak Hydrophobic Interaction Chromatography (HIC) columns are specially designed for the purification of biomolecules under conditions that promote hydrophobic interactions. These columns are pre-packed with TOYOPEARL resins that allow for the effective separation of proteins and other biomolecules based on differences in hydrophobicity. This technique is particularly valuable for purifying proteins that are sensitive to changes in pH or ionic strength, as it generally requires less rigorous conditions than other forms of chromatography.

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Features

  • Selective Binding: The HIC resins selectively bind proteins and other biomolecules based on their hydrophobic properties, offering a powerful tool for separating similar species.
  • Gentle Conditions: Operates under conditions that are less denaturing than other chromatographic methods, making it ideal for sensitive molecules.
  • Scalability: Available in a variety of sizes to facilitate process development and scale-up from research to production scales.
  • Ready-to-Use: Columns come fully equilibrated and ready for immediate application, saving valuable lab setup time.
  • Compatibility: Designed to be compatible with a wide range of chromatography systems, supporting both low and medium pressure applications.
  • Robust Design: Constructed to withstand multiple usage cycles without loss of performance, ensuring longevity and cost-effectiveness.