QLA Baskets
All pictures shown are for illustration purpose only. Actual product may vary.
QLA offers both clip on style and O-ring style baskets for most dissolution baths. Both meet the associated original equipment manufacturers dimensional specifications. Clip style baskets also comply with USP (711) specifications. All QLA Baskets are made from electropolished, sintered 316 stainless steel. The sintering process essentially creates a welded joint at each overlapping wire junction. Sintered Baskets are stronger and last longer. They retain original dimensions and geometry and resist wobble. Most conventional Baskets are not sintered and weaken over time. Critical Basket geometry is verified on an optical comparator.
Features
- All baskets are laser marked with a unique serial number and come with a Certificate of Conformance (COC) stating that they are USP compliant, where applicable, and that they meet the machine manufacturer specifications.
- A Certificate of Analysis (COA) is available at an additional cost.
- The Felodipine basket method offers a potential solution to problems associated with floating, sticking and swelling dosage forms
- Stationary baskets can be used on most dissolution testers (a modified vessel cover may be needed)
- The basket tool provides a firm grip on baskets without damage to the basket during insertion and removal from shafts
- Basket holders provide a convenient way to organise and store baskets when not in use
Specifications
Key Considerations
Mesh Openings - One of the biggest problems associated with the basket method involves the clogging of the mesh openings by particles or excipients or the random release of particles through the mesh to the bottom of the vessel. Baskets with a wide variety of mesh openings are available and if the disaggregated particle size is consistent, a variation of mesh size may solve some difficult dissolution problems.
Sintered Mesh - Every QLA stainless steel basket, that conforms to USP, is manufactured using a sintered mesh. Sintering is a strengthening process that compresses and heats the mesh under high pressures and temperatures. This results in welded joints at all the wire overlaps and adds considerable strength and longevity to the basket.
Suppository Baskets - Made from plastic, these baskets have vertical slots instead of mesh to facilitate dissolution. Blocking and/or clogging of the mesh opening is prevented by the use of such a basket, particularly when oil-based suppositories are used.
Care & Maintenance
Basket Handling - Since dissolution basket mesh is easily deformed, baskets should only be handled by the upper rim. QLA offers a special tool for installation and removal of baskets from the basket shaft.
Basket Cleaning - Care should be exercised to ensure that baskets are clean prior to use. Often the dosage form can clog the mesh which will prevent free media movement into the basket. Careful cleaning is required to ensure there is no contamination between tests.
Basket Storage - Baskets should be stored correctly to extend their life. They can frequently be found rolling around in a lab drawer! Baskets can easily be stored in the supplier’s case or using a specially designed basket holder.
