Thermo Scientific MAbPac SCX-10 Columns

Thermo Scientific MAbPac SCX-10 columns are designed specifically for high-resolution, high efficiency separation of monoclonal antibodies and their variants. The non-porous pellicular resin provides high resolution, permitting the separation of monoclonal antibody variants that differ by as little as one charge. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

The MAbPac SCX-10 columns are available in several particle sizes. 10 µm particle size columns are available in PEEK while 5 µm columns are available in both PEEK and PEEK-lined stainless steel housings for UHPLC based rapid separation (RS) applications. The MAbPac SCX-10 5 µm shorter columns are recommended for fast separations and are ideal for high throughput needs. Longer columns provide greater resolution.

The MAbPac SCX-10RS columns are packed in PEEK-lined stainless steel columns for UHPLC operating compatibility. High flow rates can be used to achieve faster mAb analysis. These RS columns are suitable for operation up to 7000 psi. The RS bioinert column bodies prevent metal interferences which can result in comprimsed mAb separations. The RS columns are designed for use with bioinert UHPLC systems.