HALO® BioClass Diphenyl Columns from Advanced Materials Technology

All pictures shown are for illustration purpose only. Actual product may vary.
HALO® Bioclass Diphenyl columns from Advanced Materials Technology come in two pore sizes of 400 Å and 1000 Å and are a valuable addition to the protein chemist’s separation toolbox for mAb realease assays and characterization methods. The HALO® Diphenyl offers a unique selectivity compared to C4 and C18 and demonstrates excellent stability with good sample recovery.
The 400 Å pore size column has a 3.4 µm superficially porous particle, whereas the 1000 Å pore size column has a 2.7 µm superficially porous particle. The columns provide narrow peak shapes and better sample recoveries for large biomolecules that range from 2 kDa and higher when compared to smaller pore sizes and fully porous particles.
Features
- HALO® 400 Å Diphenyl is ideal for large protein analysis and well suited for high speed protein separations
- HALO® 1000 Å Diphenyl is suitable for mAb analysis and offers best in class resolution for full characterization
- Alternate selectivity to HALO® C4 and HALO® ES-C18 columns
- USP designation of L11
- Available particle sizes of 2.7 µm for 1000 Å pore size and 3.4 µm for 400 Å pore size
Specifications
HALO® 400 Å Diphenyl | HALO® 1000 Å Diphenyl | |
Phase | diphenylmethyl | diphenylmethyl |
Particle Type | Fused-Core® | Fused-Core® |
Particle Size | 3.4 µm | 2.7 µm |
Pore Size | 400 Å | 1000 Å |
Endcapped | Yes | Yes |
Low pH/Temperature Limit | 2/90°C | 2/90°C |
High pH/Temperature Limit | 9/40°C | 9/40°C |
Hardware | Stainless Steel | Stainless Steel |
USP Designation | L11 | L11 |