HALO® PFP HPLC Columns from Advanced Materials Technology

The bonded, endcapped, dimethylpentafluorophenylpropyl stationary phase of HALO 90 Å PFP provides a stable, reversed phase packing with electron-deficient phenyl rings due to the presence of electronegative fluorines. In addition to forming π-π and mildly steric interactions, PFP phases also retain compounds by polar interactions. As a result of having both polar and non-polar character, PFP phases can show dual-mode retention behavior, sometimes producing a "U-shaped" retention as a function of acetonitrile content of the mobile phase, with retention increasing at both low and high concentrations of acetonitrile (reversed-phase and HILIC retention modes). HALO 90 Å PFP can be used for basic, acidic, or neutral compounds with alternate selectivity from C18.

HALO® PFP HPLC columns from Advanced Materials Technology are particularly well suited for the separation of halogenated compounds, nitro-aromatic compounds, and polar bases. Providing alternative selectivity to C18 and C8 phases, HALO® PFP columns are also compatible with highly aqueous mobile phases to facilitate the retention and separation of polar compounds. Based on Fused-Core® technology the columns are available with 2 µm, 2.7 µm, and 5 µm particle sizes for use with either UHPLC or conventional HPLC equipment.