Agilent ZORBAX Extend-C18 HPLC Columns
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Zorbax Extend-C18 HPLC Columns from Agilent
Extend-C18 columns incorporate a unique patented bidentate silane, combined with a double-endcapping process that protects the silica from dissolution at high pH - up to pH 11.5. Columns are best applied for separations of compounds that are either (1) basic and have little or no retention at low or intermediate pHs, (2) more stable or more soluble at high pH, or (3) basic and show poor peak shape at low or intermediate pH.
Agilent ZORBAX Extend-C18 HPLC columns offer high efficiency and selectivity advantages for basic compounds using high pH mobile phases up to pH 11.5. The Extend-C18 columns use a novel bidentate C18-C18 bonding technology combined with a double endcapping process to protect the silica from dissolution at high pH. This results in highly efficient separations with superior peak shape and improved resolution. Based on traditional, fully porous particles available in 1.8 µm, 3.5 µm, and 5 µm sizes for UHPLC and HPLC methods.
Features
- Robust performance and long lifetimes under high pH
- Unique bidentate bonding and double endcapping provides high pH stability
- More efficiency and better peak shape than polymer-based columns
- Improve retention, resolution and peak shape of basic compounds
- High sensitivity for LC/MS separations using ammonium hydroxide at pH 10.5
- Guards extend the lifetime of analytical columns
- USP L1 classification
- 1.8 µm RRHD columns rated to 1200 bar for highest UHPLC performance, and 1.8 µm RRHT columns ultra-fast chromatography rated to 600 bar
- 3.5 µm columns rated to 400 bar for higher resolution HPLC methods
- 5 µm columns for proven and reliable HPLC methods
- Available in 7 µm for preparative HPLC
Specifications
| ZORBAX Extend-C18 | |
| Bonded Phase | C18 |
| Particle Type | Fully Porous |
| Particle Size | 1.8 µm, 3.5 µm, 5 µm, 7 µm |
| Pore Size | 80 Å |
| Surface Area | 180 m2/g |
| Endcapped | Double |
| Carbon Load | 4% |
| Maximum Temperature | 60°C |
| pH Range | 2 - 11.5 |
| Pressure Limit | 1.8 µm RRHT - 600 bar 1.8 µm RRHD - 1200 bar 3.5 µm - 400 bar 5 µm - 400 bar |
| Hardware | Stainless Steel |
| USP Designation | L1 |
