Thermo Scientific Acclaim AmG C18 HPLC Columns

Designed to provide rugged and reproducible reversed-phase chromatography of aminoglycoside antibiotics.

Aminoglycoside antibiotics are commonly used as clinical and veterinary medicines to treat bacterial infections. HPLC using ion-pairing reversed-phase separations is an effective technique for simultaneous qualitative and quantitative determination of aminoglycosides.

The Acclaim AmG C18 column is designed to provide excellent stability, selectivity and high resolution. It has a unique surface, a polymer encapsulated silica covalently bonded with a C18 ligand. This ensures ultra-stability when exposure to low pH (<1) and high temperature conditions.

The Thermo Scientific Acclaim AmG C18 column is a high-performance silica-based C18 column specifically designed for ion-pair reversed phase HPLC analysis of aminoglycoside antibiotics. It provides exceptional performance for various aminoglycoside applications including drug purity characterization and quantification, therapeutic drug monitoring, and residual control testing in different matrices. The Acclaim AmG C18 column is based on proprietary C18 bonding technology that provides extremely high stability towards acidic conditions, high temperatures, and aqueous mobile phases.

Part Number Product Description Price Qty
product image

Features

  • Packed with polymer-encapsulated silica covalently bonded with C18 ligands to increase stability under highly acidic conditions
  • Excellent for ion-pairing aminoglycosides separations using trifluoroacetic acid (TFA)
  • Ideal for applications such as drug purity characterization and quantification, therapeutic drug monitoring, and residual control testing in different matrices

Specifications

  Acclaim AmG C18
Bonded Phase Proprietary C18
Particle Type Fully Porous
Particle Size 3 µm
Pore Size 120 Å
Surface Area 300 m2/g
Maximum Temperature <80°C
pH Range 0.5 - 10
Pressure Limit 550 bar
Hardware Stainless Steel
USP Designation L1

Literature

Rugged reversed-phase column designed for aminoglycoside antibiotics analysis
User guide for the Acclaim AmG C18 columns
Quick guide to choosing your Acclaim phase by application
Introduction to the broad range of chemistries and column families from Thermo Scientific
Selection charts based on stationary phase use, analyte properties, LC-MS requirements or USP specifications
Latest and most comprehensive range of innovative columns, accessories and equipment for fast LC, analytical HPLC and UHPLC