Thermo Scientific Acclaim HILIC-10 HPLC Columns
All pictures shown are for illustration purpose only. Actual product may vary.
Separate highly hydrophilic molecules by hydrophilic interaction liquid chromatography using Thermo Scientific Acclaim HILIC-10 LC Columns.
These columns retain and separate highly polar molecules that are unretained by reversed-phase chromatography. Their high-purity, spherical, porous silica base is covalently modified with a proprietary hydrophilic layer. This chemistry enables the use of 5–20% aqueous mobile phase while maintaining affinity for polar analytes.
Sample throughput is increased without the need to evaporate and reconstitute samples dissolved in nonaqueous solvents.
The Thermo Scientific Acclaim HILIC-10 column is designed for separating highly hydrophilic molecules by Hydrophilic Interaction Liquid Chromatography (HILIC). This column is based on high-purity spherical porous silica covalently modified with a proprietary hydrophilic layer. This chemistry enables the use of 5 – 20% aqueous mobile phase while maintaining affinity for polar analytes.
Features
- Designed with unique selectivity for hydrophilic molecules
- Retains highly polar molecules that are not retained by reversed phase chromatography
- Enhanced sensitivity for MS detection
- Hydrolytically stable
- Rugged column packing
- Broad application range, including separation of hydrophilic drugs and drug metabolites
Specifications
| Acclaim HILIC-10 | |
| Bonded Phase | Proprietary Polar Group |
| Particle Type | Fully Porous |
| Particle Size | 3 µm |
| Pore Size | 120 Å |
| Surface Area | 300 m2/g |
| Carbon Load | 8% |
| pH Range | 2 - 8 |
| Temperature Range | 70°C |
| Hardware | Stainless steel |
