Thermo Scientific MAbPac RP Columns
All pictures shown are for illustration purpose only. Actual product may vary.
The Thermo Scientific MAbPac RP columns are designed for comprehensive characterization of mAb purity by reversed-phase liquid chromatography. High resolution of intact mAb, mAb fragments such as light chain (LC), heavy chain (HC), Fc and Fab, scFc and F(ab’)2, will reveal the location, as well as nature, of modification using LC/UV or LC/MS.
The MAbPac RP column is a reversed-phase (RP) column based on a macroporous resin specifically designed for high resolution separation of intact monoclonal antibodies (mAbs) and mAb fragments. The stationary phase is fully compatible with mass spectrometry friendly organic solvents such as acetonitrile and isopropanol, as well as low pH eluents containing trifluoroacetic acid or formic acid.
Features
- Resin is based on a hydrophobic supermacroporous 4µm polymer particles
- Designed for reversed-phase biomolecule LC and LC/MS separations
- Superior resolution power for monoclonal antibodies and related substances
- High efficiency with low carry-over
- Excellent MS compatibility
- Wide operating pH range of 0 to 14
- High temperature stability up to 110°C
- Fast separations capability for high throughput separations
Specifications
| MAbPac RP | |
| Phase | Phenyl |
| Particle Type | DVB (Divinylbenzene) Polymer |
| Particle Size | 4 µm |
| Pore Size | 1500 Å |
| pH Range | 0 – 14 |
| Maximum Temperature | 110°C |
| Hardware | Stainless Steel |
| Pressure Limit | 275 bar |