Agilent AdvanceBio RP-mAb Columns
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AdvanceBio RP-mAb HPLC Columns from Agilent
Agilent AdvanceBio RP-mAb columns are designed to optimize the performance of intact and reduced mAb analysis when analyzing monoclonal antibodies for biopharma discovery, development, and QA/QC applications.
Analysis of intact and reduced monoclonal antibodies are critical measurements for characterizing therapeutic proteins and understanding their efficacy and stability. Poor chromatographic separations can result in rework and even compromise the accuracy of the characterization.
Based on Poroshell technology with unique engineering for pore size and bonded phases, AdvanceBio RP-mAb columns deliver higher resolution and faster run times to provide accurate, reproducible results. Available in a range of chemistries – SB-C8, C4, and diphenyl.
Agilent AdvanceBio RP-mAb columns are designed to optimize the performance of intact and reduced mAb analysis when analyzing monoclonal antibodies for biopharma discovery, development, and QA/QC applications. Analysis of intact and reduced monoclonal antibodies are critical measurements for characterizing therapeutic proteins and understanding their efficacy and stability. Poor chromatographic separations can result in rework and even compromise the accuracy of the characterization.
Based on Poroshell technology with unique engineering for pore size and bonded phases, AdvanceBio RP-mAb columns deliver higher resolution and faster run times to provide accurate, reproducible analysis and results. These RP-mAb columns are available in a range of chemistries – SB-C8, C4, and diphenyl.
Features
- 3.5 µm superficially porous particles with 450 Å wide pores increase mAb resolution while maintaining compatibility with all LC instruments
- Shorter analysis times compared to columns packed with fully porous particles of the same size
- Robust Poroshell packed bed and 2 µm inlet frit extend column lifetime by helping prevent inlet blockage
- Flexible method development with range of chemistries including SB-C8, C4, and diphenyl
Specifications
AdvanceBio RP-mAb C4 | AdvanceBio RP-mAb SB-C8 | AdvanceBio RP-mAb Diphenyl | |
Bonded Phase | C4 | SB-C8 | Diphenyl |
Particle Type | Superficially Porous | Superficially Porous | Superficially Porous |
Particle Size | 3.5 µm | 3.5 µm | 3.5 µm |
Pore Size | 450 Å | 450 Å | 450 Å |
Temperature Limit | 90°C | 90°C | 90°C |
pH range | 1 - 8 | 1 - 8 | 1 - 8 |
Pressure Limit | 600 bar | 600 bar | 600 bar |