GPC and SEC Columns

GPC/SEC columns are essential tools for gel permeation chromatography (GPC) and size exclusion chromatography (SEC), techniques widely used to separate molecules based on size. These columns provide accurate, reproducible data for critical polymer parameters such as dispersity (PDI), molecular weight averages, and size distribution, supporting both research and quality control in the polymer industry. 

Our portfolio includes both GPC columns for organic separations and SEC columns for aqueous and biochromatography applications. Whether analysing plastics, synthetic polymers, or biomolecules such as proteins and aggregates, our high-performance GPC/SEC columns deliver precise, reliable results across analytical and preparative workflows, ensuring confidence in molecular characterisation. 

GPC (Gel Permeation Chromatography) and SEC (Size Exclusion Chromatography) columns are essential for separating molecules by size. Aqueous SEC columns are widely used to determine molecular weight distributions of synthetic and natural water-soluble polymers. SEC columns for biochromatography applications have been optimised for the analysis of protein fragments and aggregates. Organic GPC columns are best suited for polymer and plastic analysis in organic solvents. 

Element offers a full range of aqueous and organic GPC and SEC columns from the world’s leading manufacturers, providing high-performance size-based separations at both analytical and preparative scales, in standard and high-efficiency formats.