Daicel Reversed Phase Coated Polysaccharide Chiral Columns
All pictures shown are for illustration purpose only. Actual product may vary.
Reversed Phase Columns from Daicel
Reversed phase versions have been developed by Daicel specifically for aqueous-organic mobile phases. They are suited for applications where the sample is presented in aqueous media (e.g. biological samples) or for samples that require flexibility in term of pH range. These columns are also frequently used in LC-MS applications.
Reversed phase columns include:
- CHIRALPAK AD
- CHIRALPAK AS
- CHIRALPAK AY
- CHIRALPAK AZ
- CHIRALCEL OD
- CHIRALCEL OJ
- CHIRALCEL OX
- CHIRALCEL OZ
These have the same coated chiral selector as found in the normal phase stationary phases, however in comparison, they use a different bonded silica as the base material which stabilises the CSP.
Daicel reversed phase coated polysaccharide chiral columns have been developed specifically for aqueous-organic mobile phases. They are suited for applications where the sample is presented in aqueous media (e.g., biological samples) or for samples that require flexibility in term of pH range. These columns are also frequently used in LC-MS applications.
The reversed phase coated stationary phases have the same coated chiral selector as found in the normal phase stationary phases, however, they use a different bonded silica as the base material which stabilises the stationary phase.
Available reversed phase coated polysaccharide chiral columns are:
CHIRALPAK AD – amylose tris (3,5-dimethylphenylcarbamate) chiral selector
CHIRALPAK AS – amylose tris (S)-α-methylbenzylcarbamate chiral selector
CHIRALPAK AY – amylose tris (5-chloro-2-methylphenylcarbamate) chiral selector
CHIRALPAK AZ – amylose tris (3-chloro-4-methylphenylcarbamate) chiral selector
CHIRALCEL OD – cellulose tris (3,5-dimethylphenylcarbamate) chiral selector (USP L93)
CHIRALCEL OJ – cellulose tris (4-methylbenzoate) chiral selector (USP 107)
CHIRALCEL OX – cellulose tris (4-chloro-3-methylphenylcarbamate) chiral selector
CHIRALCEL OZ – cellulose tris (3-chloro-4-methylphenylcarbamate) chiral selector
Features
- For reverse phase use with aqueous/organic mobile phases
- Traditional 10 µm, high resolution 5 µm and ultra-fast 3 µm particle sizes
- Suitable for bioanalytical applications and drug product chiral analysis
- LC-MS/MS compatible
- pH range 2 to 9
- Comprehensive screening strategies available for carrying out custom method development in-house
Specifications
| CHIRALPAK AD | CHIRALPAK AS | CHIRALPAK AY | CHIRALPAK AZ | CHIRALCEL OD | CHIRALCEL OJ | CHIRALCEL OX | CHIRALCEL OZ | |
| Chiral selector | amylose tris (3,5-dimethylphenylcarbamate) | amylose tris (S)-α-methylbenzylcarbamate | amylose tris (5-chloro-2-methylphenylcarbamate) | amylose tris (3-chloro-4-methylphenylcarbamate) | cellulose tris (3,5-dimethylphenylcarbamate) | cellulose tris (4-methylbenzoate) | cellulose tris (4-chloro-3-methylphenylcarbamate) | cellulose tris (3-chloro-4-methylphenylcarbamate) |
| USP | - | - | - | - | USP L93 | USP 107 | - | - |
| Particle size | 3, 5 µm | 3, 5 µm | 3, 5 µm | 3, 5 µm | 3, 5, 10 µm | 3, 5 µm | 3, 5 µm | 3, 5 µm |
| Type | Coated | Coated | Coated | Coated | Coated | Coated | Coated | Coated |
| Separation mode | reversed phase | reversed phase | reversed phase | reversed phase | reversed phase | reversed phase | reversed phase | reversed phase |
| Shipping solvent | Water/Acetonitrile (60/40) | Water/Acetonitrile (60/40) | Water/Acetonitrile (60/40) | Water/Acetonitrile (60/40) | Water/Acetonitrile (60/40) | Water/Acetonitrile (60/40) | Water/Acetonitrile (60/40) | Water/Acetonitrile (60/40) |
| Temperature range | 0 - 40°C | 0 - 40°C | 0 - 40°C | 0 - 40°C | 0 - 40°C | 0 - 40°C | 0 - 40°C | 0 - 40°C |
