Daicel Chiral Zwitterionic Chiral Columns
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Daicel zwitterionic chiral columns CHIRALPAK ZWIX(+) and ZWIX(-) are packed with zwitterionic chiral stationary phases. These novel selectors incorporate both anion- and cation-exchange functional groups. They are designed for separation of zwitterionic molecules, such as underivatized amino acids and small peptides. The elution order of enantiomers can be systematically reversed on CHIRALPAK ZWIX(+) and CHIRALPAK ZWIX(-), although their column performance may not be exactly equal towards each analyte.
CHIRALPAK ZWIX(+) - quinine-derived (8S, 9R) chiral selector
CHIRALPAK ZWIX(-) - quinidine-derived (8R, 9S) chiral selector
Features
- Specialty phases for amino acids and zwitterionic compounds
- Compatible with HPLC (polar organic phase and hydro-organic phase) and SFC applications
- Compatible with all common HPLC solvents
- Suitable for use in LC-MS detection
Specifications
| CHIRALPAK ZWIX(+) | CHIRALPAK ZWIX(-) | |
| Chiral selector | quinine-derived (8S, 9R) | quinidine-derived (8R, 9S) |
| Particle size | 3 and 5 µm | 3 and 5 µm |
| Type | Immobilised | Immobilised |
| Separation mode | Polar organic phase and hydro-organic phase HPLC and SFC | Polar organic phase and hydro-organic phase HPLC and SFC |
| Shipping solvent | 100% Methanol | 100% Methanol |
| Temperature range | 5 to 45°C | 5 to 45°C |
Literature
Structures of commercially available Daicel chiral stationary phases
Catalogue of part numbers for Daicel columns
Screening strategies for zwitterionic columns to identify the best method to separate target compounds