YMC Guard Cartridge Holders and Column Couplers

Guard Cartridge Holders from YMC Europe GMBH

YMC offers various different guard cartridge holder concepts for UHPLC, analytical and semi-prep.

    YMC offer a UHPLC guard cartridge holder (XPCHUHP for 5 mm cartridges). The UHPLC holder has a zero-dead-volume direct connection to column to minimize the impact on separation. The guard cartridge holder is stable at high pressures up to 1000 bar (15,000 psi).

      The universal finger tight system is for all column internal diameters from 1 to 4.6 mm id (XPGCH-Q1 for 10 mm cartridges and XPGCH-Q2 for 20 mm cartridges). This system guarantees a low dead volume connection between the guard cartridge and the main column irrespective of the type of column fitting used. The guard cartridge holder gives leak-proof connection to the analytical column up to 420 bar (6,000 psi).

        YMC offers a specific integral guard cartridge holder (XPGCS-Q1 for 10 mm and XPGCS-Q2 for 20 mm length cartridges with 1, 2.1 3 or 4 mm inner diameters). This holder is screwed directly on the YMC cartridge column system in place of the removable end fitting (part numbers ending in QT). The guard cartridges are inserted in the holder cavity without the need to use any tools. These integral guard cartridge holders will not attach to columns with part numbers ending in WT or PT.

          For semi-prep columns several guard holders are available. As the holder for these cartridges feature Parker-compatible fittings (port depth 0.09 inch). It is essential that slip-free fittings are used or specially made stainless steel fittings with stainless steel capillaries are made up so that differences between Valco-compatible (port depth 0.08 inch), Parker-compatible (port depth 0.09 inch) and/or Waters-compatible (port depth 0.13 inch) column endfittings can be accommodated. Due to the higher flowrates involved in semi-prep and prep chromatography the use of PEEK capillaries should be avoided if possible. The part number of semiprep guard cartridges ends -CC. The part numbers for the guard cartridge holders are XPCHSPW1 (10 mm i.d.), XPCHSPW2 (20 mm i.d.) or XPCHSPW3 (30 mm i.d.).

YMC guard cartridge holders are used to connect YMC guard cartridges to LC columns to help extend the lifetime of the column. Column couplers are used to connect stand-alone holders to the columns. Various formats are available for UHPLC, analytical and semi-prep guard cartridges.

UHPLC guard cartridges with 1.9 µm particle size are designed to be used with the UHPLC holder. Designed to connect directly to the UHPLC column to reduce extra column effects while meeting the demands of extreme pressure up to 1400 bar.

For analytical guard cartidges with internal diameters of 1.0 – 4.6 mm there are two guard cartridge holders available depending on which length guard cartridge is used. The holder for the 10 mm length cartridges consists of a holder and connector. For 20 mm length cartridges, the holder is combined with a MarvelX universal connector. Both systems guarantee a low dead volume connection between the guard cartridge and the main column.

Semi-prep guard cartridges come in 10 x 10 mm ID, 10 x 20 mm ID, and 10 x 30 mm ID sizes, with separate holders available for each internal diameter. The constructed guard and holder can be attached to the main column with a column coupler.

Part Number Product Description Price Qty
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Features

  • All YMC guard cartridges require to be used with a guard holder
  • Holders available for UHPLC guard cartridges, standard HPLC guard cartridges, and semi-prep guard cartridges
  • Separate holders available for 10 mm and 20 mm analytical guard cartridges
  • Choose the holder based on the internal diameter of the guard cartridges
  • Column couplers are used to connect stand alone guard holders to the main column   

Literature

Review of the different types of column hardware and phases provided by YMC
Best practice for using the YMC UHPLC guards and holder
Guide to using the YMC analytical guard cartridges and holder
How to install the YMC semi-prep guard cartridges