HELIX Coresep S HPLC Columns

Coresep S is a normal-phase analytical column with embedded acidic ion-pairing groups embedded on core-shell particles.

  • Most suitable for separation of common sugars and other neutral or very polar molecules.
  • Retains and separates compounds based on HILIC, cation-exchange and anion-exclusion modes Retains and separates amino acids with different buffers at low concentration.
  • Separates weak bases by ion-exchange mechanism. Separate acids by ion-exclusion mechanism.
  • All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 2.0 to 7.0)..

HELIX Coresep S is a bi-modal HPLC column with HILIC and medium strength cation-exchange properties, based on core-shell particles. Designed to retain and separate hydrophilic neutral, hydrophilic acidic and basic, zwitterionic compounds in HILIC, cation-exchange, and anion-exclusion modes. Typical applications include the analysis of metabolomic compounds, analysis of hydrophilic and hydrophobic drugs and counter-ions in the same run, and the analysis of lipids.

Part Number Product Description Price Qty
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Features

  • Coresep S is a normal-phase column with embedded acidic ion-pairing groups embedded on core-shell particles
  • Suitable for the separation of common sugars and other neutral or very polar molecules
  • Retains and separates compounds based on HILIC, cation-exchange and anion-exclusion modes
  • Retains and separates amino acids with different buffers at low concentration
  • Separates weak bases by ion-exchange mechanism
  • Separate acids by ion-exclusion mechanism
  • All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 2.0 to 7.0)
  • Coresep range also includes Coresep SB with reversed phase and strong anion-exchange properties, and Coresep 100 with reversed phase and medium cation-exchange properties

Specifications

  Coresep S
Mode Mixed-Mode
Phase Type Normal phase column with embedded acidic ion-pairing groups on core-shell particles
Particle Type Solid Core
Particle Size 2.7 µm
Pore Size 90 Å
Temperature Range 20 - 60°C
pH Range 2 - 7
Pressure Limit 1000 bar