InfinityLab Preparative HPLC Columns from Agilent
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Any purification campaign centers around three objectives – yield, purity, and throughput. Agilent InfinityLab preparative LC columns are optimized to help you to achieve your goals. Available in a variety of media, such as Pursuit XRs with high loading capacity, Zorbax with diverse selectivity, or Poroshell 120 with high speed and efficiency, these columns offer a suitable fit for your purification needs. Agilent InfinityLab preparative LC columns are available in 21.2 and 30 mm internal diameters and easily scale from analytical dimensions.
Features
- Easy scale-up from analytical to preparative scale
- Average particle size is either 4 µm for Poroshell 120, or 5 µm for Zorbax and Pursuit XRs
- Maximum operating pressure is 400 bar (6,000 psi)
- InfinityLab Poroshell prep columns deliver higher performance at higher flow rates — without sacrificing loadability — when resolution and speed are most critical
- With its high surface area and carbon load, InfinityLab Pursuit XRs offers excellent loadability and retention so you can purify more product per injection
- InfinityLab ZORBAX preparative columns scale from our most popular ZORBAX phases, with chemistries in a range of dimensions
- InfinityLab preparative LC columns are produced using the same particle and bonding technology employed in the production of analytical scale packings.
- Columns are loaded to a stable, uniform bed density using an optimized proprietary high‑pressure slurry-loading technique to give maximum column efficiency
Specifications
InfinityLab Preparative LC Column Specifications
|
Objective |
Phase | Pore Size | pH Range | Endcapped | Carbon Load | Surface Area | Benefits and Applications |
| Throughput | Poroshell 120 SB-C18 | 120 Å | 1.0 – 8.0 | No | 9% | 130 m2/g | Best for low pH |
| Poroshell 120 HPH-C18 | 100 Å | 2.0 – 11.0 | Double | Proprietary | 95 m2/g | Best for high pH | |
| Alternate Selectivity for High Throughput or Yield |
ZORBAX Eclipse Plus C18 | 95 Å | 2.0 – 9.0 | Double | 9% | 160 m2/g | General purpose starting point similar selectivity to HPH-C18 |
| ZORBAX Eclipse Plus C8 | 95 Å | 2.0 – 9.0 | Double | 7% | 160 m2/g | Lower retention of hydrophobic analytes vs C18 | |
| ZORBAX SB-C18 | 80 Å | 0.8 – 8.0 | No | 10% | 180 m2/g | Best for low pH | |
| ZORBAX SB-C8 | 80 Å | 1.0 – 8.0 | No | 6% | 180 m2/g | Lower retention of hydrophobic analytes vs C18 | |
| ZORBAX Eclipse Plus Phenyl-Hexyl | 95 Å | 2.0 – 8.0 | Double | 9% | 160 m2/g | Alternate selectivity for aromatic compounds | |
| Yield | Pursuit XRs C18 | 100 Å | 1.5 – 10.0 | Yes | 22% | 440 m2/g | Maximum loadability |
| Pursuit XRs C8 | 100 Å | 1.5 – 10.0 | Yes | 15% | 440 m2/g | Maximum loadability; lower retention of hydrophobic analytes vs C18 | |
| Pursuit XRs Diphenyl | 100 Å | 1.5 – 7.5 | Yes | 14.6% | 440 m2/g | Maximum loadability; alternate selectivity for aromatic compounds |
Literature
Maximize purity, throughput, and yield
Take your throughput to new levels
Save time from analytical to preparative with superficially porous particle technology
A tale of two samples: understanding the purification workflow from different perspectives. Part 1: bulk purification
A tale of two samples: understanding the purification workflow from different perspectives. Part 2: high-throughput purification
Higher efficiency and sample loading capacity yield greater return on investment with InfinityLab Poroshell 120 Preparative LC Columns
General information for all ZORBAX, Poroshell, Pursuit, and Polaris reversed-phase columns