Silicycle SiliaPrep Mixed-Mode SPE

Silicycle SiliaPrep mixed-mode SPE phases are used for the extraction of acidic and basic compounds from aqueous solutions. The mixed-mode SPE is based on a dual retention mechanism of non-polar and ion-exchange. Various sorbents are available to suit different application types.

SiliaPrep C8/SAX and SiliaPrep C8/SAX-2 mixed-mode sorbents are used to extract acidic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.

SiliaPrep C8/SCX and SiliaPrep C8/SCX-2 mixed-mode sorbents are used to extract basic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.

SiliaPrep C8/SCX-2/SAX and SiliaPrep C8/SCX-2/SAX-2 are a tri-mode extraction and allows fractionation of acidic, neutral, and basic compounds from aqueous solutions, typically drugs and metabolites from physiological fluids.

SiliaPrep SCX-2/SAX is a mixed-mode sorbent used to separate acidic and basic molecules from non-ionisable molecules.

Part Number Product Description Price Qty
product image

Features

  • SiliaPrep Mixed-Mode is based on dual retention mechanism of non-polar and ion-exchange
  • Excellent separation due to narrow particle size distribution and no fines
  • High recovery and yield
  • Reproducible flow rates from lot-to-lot
  • Available in different formats including SPE cartridges and 96 well plates
  • Standard SiliaPrep cartridges are made with flanged polypropylene (PP) tubes and 20 μm polyethylene (PE) frits

Specifications

  SiliaPrep C8/SAX SiliaPrep C8/SAX-2 SiliaPrep C8/SCX SiliaPrep C8/SCX-2 SiliaPrep C8/SCX-2/SAX SiliaPrep C8/SCX-2/SAX-2 SiliaPrep SCX-2/SAX 
Support Backbone Silica Gel Silica Gel Silica Gel Silica Gel Silica Gel Silica Gel Silica Gel
Phase C8 and TMA Chloride (SAX) C8 and TMA Acetate (SAX-2) C8 and Tosic Acid (SCX) C8 and Propylsulfonic Acid (SCX-2) C8, Propylsulfonic Acid (SCX-2), and TMA Chloride (SAX) C8, Propylsulfonic Acid (SCX-2), and TMA Acetate (SAX-2) Propylsulfonic Acid (SCX-2) and TMA Chloride (SAX)
Particle Shape Irregular Irregular Irregular Irregular Irregular Irregular Irregular
Particle Size 40 - 63 µm 40 - 63 µm 40 - 63 µm 40 - 63 µm 40 - 63 µm 40 - 63 µm 40 - 63 µm
Pore Size 60 Å 60 Å 60 Å 60 Å 60 Å 60 Å60 Å  

Literature

Solutions for sample preparation from Silicycle
Silica based SPE cartridges and well plates from Silicycle