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HALO® BioClass Glycan Columns from Advanced Materials Technology

The HALO 90 Å Glycan stationary phase is a highly polar ligand that possesses 5 hydroxyl groups tethered to the silica via novel proprietary linkage chemistry. This high performance material provides a column that can be used with the typical mobile phases for hydrophilic interactive liquid chromatography (HILIC) of oligosaccharides and particularly for protein-linked glycans.

HALO® BioClass Glycan columns from Advanced Materials Technology incorporate a highly polar ligand that contains five hydroxyl groups tethered to 2.7 μm Fused-Core® silica particles via novel, proprietary linkage chemistry. This column can provide high-resolution separations of complex glycan mixtures using HILIC method conditions.

Part Number Product Description Price Qty
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Features

  • Each lot of HALO® Glycan material is quality assurance tested for application performance
  • Ideal for HILIC separations of oligosaccharides, and particularly, of released and labeled glycans from glycoproteins and proteoglycans
  • A highly polar ligand that contains 5 hydroxyl groups tethered to 2.7 µm Fused-Core® silica particles via novel, proprietary linkage chemistry
  • Improved retention of acidic and zwitterionic analytes
  • USP L95 designation
  • Particle size of  2.7 µm

Specification

  HALO® 90 Å Glycan
Phase Proprietary hydrophilic ligand
Particle Type Fused-Core®
Particle Size 2.7 µm
Pore Size 90 Å
Endcapped No
Low pH/Temperature Limit 2/65⁰C
High pH/Temperature Limit 9/40⁰C
Hardware Stainless Steel
USP Designation L95

Literature

HALO® columns for protein, peptide and glycan applications
A better path to separations with Fused-Core®
HALO® guard columns provide optimum protection for your HALO® HPLC and UHPLC column without sacrificing column efficiency