HELIX Coresep SB HPLC Columns
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Coresep SB Columns from HELIX
Coresep SB is a reverse-phase analytical column with strong embedded basic ion-pairing groups embedded on core-shell particles.
- Improves retention of acidic compounds by anion-exchange mechanism.
- Separates bases by ion-exclusion mechanism.
- Retains neutral compounds by reverse-phase mechanism.
- All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 1.5 to 5).
Coresep SB from HELIX is a bi-modal HPLC column with reversed-phase and strong anion-exchange properties based on core-shell particles. Designed to retain and separate hydrophobic basic, hydrophobic neutral, hydrophilic acidic, hydrophilic acidic small and medium sized molecules. Typical applications include the separation of basic, analysis of basic hydrophobic drugs and acidic counter-ions in one run, and separation of ionisable structural isomers.
Features
- Coresep SB is a reverse-phase column with strong embedded basic ion-pairing groups embedded on core-shell particles
- Improves retention of acidic compounds by anion-exchange mechanism
- Separates bases by ion-exclusion mechanism
- Retains neutral compounds by reverse-phase mechanism
- All mobile phases are LC-MS and preparative chromatography compatible (working pH range from 1.5 to 5)
- Coresep range also includes Coresep S with HILIC and medium cation-exchange properties, and Coresep 100 with reversed phase and medium cation-exchange properties
Specifications
| Coresep SB | |
| Mode | Mixed-Mode |
| Phase Type | Reversed phase column with embedded strong basic ion-pairing groups on core-shell particles |
| Particle Type | Solid Core |
| Particle Size | 2.7 µm |
| Pore Size | 90 Å |
| Temperature Range | 20 - 60°C |
| pH Range | 1.5 - 5 |
| Pressure Limit | 1000 bar |
Literature
Coresep SB – reversed phase anion exchange column for unique selectivity, efficiency and speed