Imtakt Scherzo SS-C18 HPLC Columns
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Imtakt Scherzo SS-C18 columns belong to the Scherzo family of mixed-mode columns with reversed phase, anion exchange, cation exchange, and normal phase functionalities. Three subtly different but complementary columns have been developed by varying the chemistry of the anion and cation exchange functional groups, and the density of each group on the silica surface.
The Scherzo SS-C18 column contains a C18 chain supplemented with a high density of strong anion exchange (SAX) and strong cation exchange (SCX) groups. The strong ionic character of this phase enhances the retention of weakly ionised compounds, as well as zwitterions.
Features
- Large amount of strong ionic ligands, effective for improved retention of zwitterions or weak ionic compounds
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Wide range of method development possibilities
- Can simultaneously optimise organic, buffer, and pH gradients
- Scherzo range also includes Scherzo SW-C18 for strong ionic compounds and Scherzo SM-C18 for the separation of basic/acidic compounds at neutral pH
Specifications
| Scherzo SS-C18 | |
| Mode | Mixed-Mode |
| Phase Type | C18 with large amounts of strong anion and strong cation groups |
| Particle Type | Fully Porous |
| Particle Size | 3 µm |
| Pore Size | 130 Å |
Literature
Scherzo C18 family - three kinds of C18 column with different ion exchange capacities