SiELC Primesep D HPLC Columns

SiELC Primesep D is a mixed-mode HPLC column specifically designed for direct plasma analysis, featuring basic ion-pairing groups embedded into long ligand chains. It retains hydrophobic and acidic components, while excluding high-molecular weight plasma components. Primesep D has a working pH range of 1.5 to 4 and offers mobile phase compatibility with low UV detection, LC-MS, and preparative chromatography.

Part Number Product Description Price Qty
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Features

  • Primesep C is a mixed-mode HPLC column specifically designed for direct plasma analysis
  • It features basic ion-pairing groups embedded into long ligand chains
  • Retains hydrophobic and acidic components
  • Excludes high-molecular weight plasma components
  • Offers mobile phase compatibility with LC-MS
  • Resistant to dewetting in 100% aqueous mobile phase
  • Scalable from capillary to prep
  • Guard columns connect directly to columns and do not require any additional holders

Specification

  Primesep D
Mode Mixed-Mode
Phase Type Basic ion-pairing groups embedded in long ligand chains
Particle Type Fully Porous
Particle Size 5 µm
Pore Size 100 Å
Temperature Range 0 - 50°C
pH Limit 1.5 - 5.0
Recommended pH Operating Range 2.0 - 4.5
Pressure Limit 345 bar

Literature

Creating new dimensions in the world of chromatography
Solving problems of pharmaceutical HPLC analysis using Primesep columns
New alternative to ion chromatography