Thermo Scientific Acclaim Trinity P2 HPLC Columns
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Thermo Scientific Acclaim Trinity P2 HPLC columns are an innovative, mixed-mode column technology providing HILIC, anion-exchange, and cation-exchange functionalities for flexible method development. Mixed-Mode combinations allow the chromatographic conditions to be easily modified to optimise selectivity by adjusting either mobile phase ionic strength, pH and/or organic solvent concentration. The Acclaim Trinity P2 columns are designed to separate pharmaceutical counterions, including monovalent and divalent cations or anions.
Features
- Mixed-mode column technology combining HILIC, anion exchange and cation exchange
- Inner-pore area consists of the bi-modal hydrophilic surface together with cation exchange retention, while the outer surface is modified with anion-exchange nano-polymer beads
- Ideal for separating pharmaceutical counterions, including monovalent and divalent cations or anions
- Low column bleed; compatible with mass spectrometry (MS) and charged aerosol detection (CAD)
- Hydrolytically stable
- Use alongside the Acclaim Trinity P1 to provide a total solution for pharmaceutical couterion analysis by HPLC
Specification
| Acclaim Trinity P2 | |
| Mode | Mixed-Mode |
| Phase Type | Trimode phase containing SCX, WAX and HILIC functionalities |
| Particle Type | Fully Porous |
| Particle Size | 3 µm |
| Pore Size | 300 Å |
| Surface Area | 100 m2/g |
| Temperature Limit | 45°C |
| pH Limit | 2.5 - 7.0 |
| Pressure Limit | 415 bar |
Literature
Introduction to the broad range of chemistries and column families from Thermo Scientific
Columns for challenging separation needs
Ideal solution for pharmaceutical counterion analysis
User guide for the Acclaim Trinity P2 columns
Quick guide to choosing your Acclaim phase by application