Thermo Scientific Syncronis HILIC HPLC Columns
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Thermo Scientific Syncronis HILIC HPLC columns ensure consistent and predictable separations of polar and hydrophilic analytes. Highly pure, high surface area silica and dense stationary phase coverage minimises secondary interactions and provides reproducible high-resolution separations. The zwitterionic stationary phase results in a neutral, highly polar surface and provides alternative selectivity to C18 columns without ion-pairing or derivatization. The highly organic mobile phases used with Syncronis HILIC columns increases desolvation efficiency in MS detection.
Features
- Provides enhanced retention of polar and hydrophilic analytes
- Sulfobetaine zwitterion has both positive (quaternary ammonium) and negative (sulfonic acid) groups in a 1:1 ratio, so the net charge is zero
- Dense surface coverage of silica minimizes secondary interactions and peak tailing
- Highly pure, high surface area silica particles
- Outstanding peak shape and sensitivity
- Manufactured, packed and tested in ISO-9000-accredited facilities
- 1.7 µm for rapid UHPLC separations, 3 µm and 5 µm for traditional HPLC analysis
Specifications
| Syncronis HILIC | |
| Bonded Phase | Zwitterionic |
| Particle Type | Fully Porous |
| Particle Size | 1.7 µm, 3 µm, 5 µm |
| Pore Size | 100 Å |
| Surface Area | 320 m2/g |
| Endcapped | No |
| Carbon Load | 5% |
| Maximum Temperature | 60°C |
| pH Range | 2 - 8 |
| Pressure Limit | 3 µm and 5 µm - 400 bar 1.7 µm - 1250 bar |
| Hardware | Stainless Steel |
Literature
Enhanced retention of polar and hydrophilic analytes using Thermo Scientific Syncronis HILIC columns
Remarkable separations guaranteed time after time
Practical guide to HILIC mechanisms, method development and troubleshooting
Latest and most comprehensive range of innovative columns, accessories and equipment for fast LC, analytical HPLC and UHPLC
Selection charts based on stationary phase use, analyte properties, LC-MS requirements or USP specifications