YMC-Pack Pro C18RS HPLC Columns

YMC-Pack Pro C18 RS Analytical HPLC Columns

The relatively high carbon load of 22% for YMC-Pack Pro C18 RS and its smaller pore diameter amplifies the selectivity’s ability to discriminate between closely related compounds such as positional or steric isomers. YMC-Pack Pro C18 RS recognises even slight steric differences, even if the analytes differ only in their three-dimensional structure and not in their hydrophobicity or polarity. A more conventional carbon load (~15%) C18 chemistry is not able to use this property for separation.

YMC-Pack Pro C18 RS columns are engineered to provide exceptional resolution and selectivity making them especially suitable for separating structurally similar compounds. The enhanced steric selectivity offered by the high carbon load of 22% and smaller pore size of 80 Å makes this column ideal for complex mixtures where resolution of closely related analytes is challenging. With a broad pH range of 1 – 10, the YMC-Pack ProRS columns provide flexible method development opportunities for demanding applicaitons.

Part Number Product Description Price Qty
product image

Features

  • Endcapped C18 stationary phase with USP L1 classification
  • High carbon loading at 22%  offers superior hydrophobicity and steric selectivity crucial for resolving closely related structural isomers
  • Stable across a pH range from 1.0 to 10.0 making to suitable for highly acidic to highly basic conditions
  • Robust bonding technology ensures that the columns are highly durable and provide consistent performance over extended periods of use
  • Delivers sharp peak shapes and excellent resolution, particularly valuable for complex pharmaceutical, environmental, and biochemical analyses
  • Available in fully porous particle sizes of 3 µm and 5 µm, and fully scalable from microbore up to preparative dimensions
  • Guard columns protect the analytical column and help to prolong its lifetime

Specifications

  YMC-Pack Pro C18RS
Bonded Phase C18
Particle Type Fully Porous
Particle Size 3 µm, 5 µm
Pore Size 80 Å
Surface Area 510 m2/g
Endcapped Yes
Carbon Load 22%
Maximum Temperature 50°C
pH Range 1 - 10
Hardware Stainless Steel
USP Designation L1

Literature

Full details on the YMC classic range of HPLC columns
YMC columns for reversed phase HPLC and UHPLC