Reversed Phase HPLC Columns

Reversed phase HPLC columns are the most widely used separation mode in liquid chromatography, providing versatile solutions for a broad range of analytical challenges. Element Lab Solutions offer a wide range of reversed phase HPLC and UHPLC columns designed to deliver robust, reproducible separations across diverse applications. 

These columns typically use hydrocarbon chains of varying lengths, such as C18, C8, and C4. Further modifications – such as polar endcapping or polar embedded functional groups – enhance retention of polar compounds, while phenyl and PFP phases are ideal for aromatic analytes. Available in fully porous silica, solid-core silica, and polymer-based materials, each reversed phase chromatography column is designed to optimise retention, resolution, and efficiency.  

Reversed phase HPLC and UHPLC columns come in a wide variety of stationary phases for tackling many different separation challenges. Reversed phase columns typically feature a hydrocarbon chain that varies in length, such as C18, C8, C4, and C30. Further modifications such as polar endcapping or polar embedded functional groups provide enhanced retention of polar compounds, and phenyl and PFP are recommended for aromatic compounds. The columns are manufactured in a wide variety of dimensions with either traditional fully porous silica, or solid-core silica for increased efficiency at lower pressures.