Porvair Microlute® CSi Ion Exchange SPE Plates

The Microlute® CSi ion exchange phases, SAX (strong anion exchange) and SCX (strong cation exchange), utilise Porvair Sciences' innovative composite silica technology to provide enhanced sample cleanup and analyte recovery. The SAX phase, featuring a positively charged quaternary amine functional group, is ideal for retaining weak acids (pKa > 3), while the SCX phase, with a negatively charged aromatic sulfonic acid group, effectively captures weak bases (pKa < 11). Both phases are available in a 96-well plate format, designed to provide uniform flow through each well, improving reproducibility and minimising variability in recovery. The robust porous structure of the Microlute® CSi enhances method consistency, making it automation-friendly and ideal for seamless method transfer in ion exchange SPE applications.

Part Number Product Description Price Qty
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Features

  • Silica-Based Ion Exchange Format – Designed for preparation and analysis of ionic analytes
  • Microlute® CSi SAX – Positively charged quaternary amine functionality, optimised for weak acids (pKa > 3)
  • Microlute® CSi SCX – Negatively charged aromatic sulfonic acid functionality, ideal for weak bases (pKa < 11)
  • Composite Technology – Porous polymer structure combined with silica for improved consistency and performance
  • Improved Reproducibility – Delivers reliable recovery of analytes across multiple samples
  • Uniform Flow – Maintains consistent liquid distribution through each well, reducing variability
  • 96-Well Plate Options – Available in 2 mg or 10 mg bed weights to match different application needs
  • Extended Range – Microlute® CSi also available in reversed-phase C18 and polymeric Microlute® CP format

Specification

  Microlute® CSi SAX Microlute® CSi SCX
Retention Mechanism Strong anion exchange Strong cation exchange
Analyte Retention Acidic analytes Basic analytes
Base Material Silica Silica
Composite Material Polyethylene (Medical grade) Polyethylene (Medical grade)
Ligand Quaternary amine Aromatic sulphonic acid
Bed Weight 2 mg and 10 mg 2 mg and 10 mg
Format 96 Well Plate 96 Well Plate
pH Range 2 - 9 2 - 9

Literature

Innovative range of sample preparation products from Porvair Sciences
Improve consistency and reproducibility using composite silica SPE plates
Evaluation of a novel composite silica technology for solid phase extraction
Advice for using Porvair Microlute® SPE