Advion-Interchim puriFlash 5.030

The puriFlash 5.030 from Advion-Interchim Scientific is a high-performance flash chromatography system designed for Ultra Performance Flash Purification (UPFP). With a flow rate capacity of up to 300 mL/min, it supports a broad range of column formats (F0004 to F0800), enabling fast, efficient separations across various compound classes. Pairing with 15 µm columns allows higher flow rates with minimal efficiency loss, significantly reducing purification time.

Automation is central to the system's design. Integrated features include RFID column recognition, solvent level monitoring, and leak detection, enhancing both safety and reproducibility. The optional 4-way injection valve and dry-load kit further streamline workflow by enabling automated solid-phase injections and sample preparation during equilibration.

Detection is robust, with triple-mode UV, ELS, and mass detection ensuring accurate compound identification. The ClearPeak software continuously monitors system performance and incorporates an AI assistant (Genius) to suggest purification methods based on TLC input—transferable via smartphone. The system is operable via a 15″ touchscreen and supports remote monitoring, offering flexibility and control.

Compact and efficient, the puriFlash 5.030 does not require placement in a fume hood when used with the optional enclosure, making it ideal for space-conscious laboratories requiring reliable, automated purification.

Features

  • ClearPeak Software Control – Full system management with intuitive interface for method development, monitoring, and automation
  • TLC to Flash & Prep App Compatibility – Seamless method transfer from TLC plates via smartphone integration
  • 15” Touchscreen & Remote Monitoring – Large interactive display with remote access for flexible operation
  • UV Detection (200–400 nm) – Multi-wavelength and collective scanning for accurate compound tracking
  • Wide Column Compatibility – Supports all flash column formats from F0004 to F0800 for versatile purification needs
  • High-Capacity Rack System – Accommodates 3 long racks with up to 132 test tubes for extended runs
  • High Flow Rate – Delivers up to 300 mL/min for rapid separations without compromising performance
  • Robust Pressure Handling – Operates up to 30 bar to support a broad range of purification conditions

Specifications

  puriFlash 5.030
Pump  
Flow rate 300 mL/min
Max pressure 30 bar
Quaternary gradient yes
Air purge yes
Washing discs no
Pump washing discs (pack) no
   
Detector  
UV: 200 - 400 nm multi wavelength & scan collection yes
UV: 200 - 800 nm multi wavelength & scan collection pack-UVextended
Spectral view and purity confirmation yes
iELSD Detection (pack) pack-iELSD
   
Injection  
4 port electrical valve pack 4-ways electroc valve
6 port electrical valve with loop no
6 port + 10 port electrical valves with loop no
Injection mode: liquid - dry-load yes
   
Column Selection Valve  
6 port electrical valve no
   
System Optimisation  
Tubing after pump 1/8" x 1.6 mm ID
Flow cell: optical length/volume 0.1 mm/40 µL
   
Column Holder  
Integrated yes
Pre-column holder yes
   
Fraction Collector  
Reglular collector 3 racks Gen5
132 tubes 18 x 150 mm
   
Unit Control  
Touch screen 15" yes
USB 8
RJ45 yes
   
Safety  
Leak detection (pump, FC, iELSD, holders) yes
Solvent tray with drainage system yes
Collector with drainage system yes
Solvent and waste level monitoring yes
RFID yes
Fume enclosure yes
   
Size Width: 40 cm
Depth: 51 cm
Height: 75 cm

Literature

The essential systems and consumables for purification, evaporation, and mass spectrometry
puriflash 5.030 - Optimised for Ultra Performance Flash Purification