The Uptisphere Strategy flash columns from Advion-Interchim Scientific offer a versatile, high-performance solution for flash chromatography, optimising compound purification across a wide range of chemical classes. Manufactured with high-purity silica phases, these columns deliver superior selectivity, high loading capacity, and consistent reproducibility. The portfolio includes four tailored chemistries – C18-HQ, PHC4, HILIC-HIA, and HILIC-HIT – providing optimal performance for purifying non-polar, aromatic, and highly polar compounds alike. Whether for routine pharmaceutical methods or complex separations, Uptisphere Strategy columns enable efficient purification workflows.

Each phase within the Uptisphere Strategy portfolio offers unique capabilities to match specific purification needs:

• Uptisphere Strategy C18-HQ: Ideal for the purification of non-polar to moderately polar compounds, this high-quality C18 phase delivers excellent retention, high resolution, and robust reproducibility in reversed phase conditions
• Uptisphere Strategy PHC4: Designed for aromatic and polyaromatic compounds, this phenyl-butyl phase offers enhanced π–π interactions and versatile retention under reversed phase conditions
• Uptisphere Strategy HILIC-HIA: Optimised for highly polar analytes, this HILIC phase enables efficient retention and separation of polar compounds that are poorly retained in reversed phase chromatography, making it ideal for polar molecules
• Uptisphere Strategy HILIC-HIT: A complementary HILIC phase that provides alternative selectivity for polar compounds, offering balanced retention characteristics and robust performance under aqueous-organic mobile phase conditions