Advion-Interchim puriFlash 5.250
The puriFlash 5.250 flash system from Advion-Interchim Scientific is a compact yet highly versatile purification system designed to meet a wide range of chromatographic requirements, from routine separations to complex, high-sensitivity purifications. Supporting both normal and reverse phase applications, as well as flash chromatography and preparative HPLC, it offers a flexible platform well-suited to synthetic, analytical, and process development laboratories.
With a maximum flow rate of 250 mL/min and an operating pressure of up to 250 bar, the system is capable of handling both low- and high-complexity samples efficiently. This makes it particularly valuable for tasks such as impurity profiling, trace enrichment, and the purification of minor components.
The puriFlash 5.250 incorporates triple detection capability – UV, ELSD, and MS – to ensure accurate identification and recovery of target compounds, including those present at low concentrations. The enhanced detection sensitivity supports comprehensive fraction collection, reducing the risk of overlooking critical components.
Designed for continuous operation with minimal maintenance, the puriFlash 5.250 includes built-in safeguards such as RFID component recognition and leak detection to enhance safety and reduce setup errors. System control is handled via a 15″ touchscreen with ClearPeak software and Genius automation, enabling remote access, method transfer, and purification setup based on TLC or analytical data – streamlining workflows and improving overall efficiency.
Combining performance, adaptability, and intelligent automation, the puriFlash 5.250 is a robust solution for laboratories requiring dependable, high-throughput purification across a diverse range of applications.
All pictures shown are for illustration purpose only. Actual product may vary.
Features
- ClearPeak Software Control – Comprehensive system management with an intuitive interface for method setup and monitoring
- TLC to Flash & Prep App Compatibility – Enables direct method transfer from TLC analysis to flash or preparative chromatography via smartphone integration
- 15″ Touchscreen with Remote Monitoring – Large display for real-time control and system oversight, locally or remotely
- UV Detection (200–400 nm) – Multi-wavelength and collective scan functionality for precise, flexible compound detection
- Wide Column Compatibility – Supports both flash and preparative columns with inner diameters up to 80 mm
- High-Capacity Rack System – Accommodates 3 long racks and up to 132 tubes for extended fraction collection
- Maximum Flow Rate – 250 mL/min for high-throughput purification
- Maximum Operating Pressure – 250 bar for use with high-efficiency columns and complex separations
- Upgradeable Performance Packs – Optional ‘UVextended’, ‘iELSD’, ‘Multi’, and ‘PWD’ modules available to enhance detection and purification capabilities
Specification
| puriFlash 5.250 | |
| Pump | |
| Flow rate | 250 mL/min |
| Max pressure | 250 bar |
| Quaternary gradient | yes |
| Air purge | yes |
| Washing discs | yes |
| Pump washing discs (pack) | pack-PWD |
| Detector | |
| UV: 200 - 400 nm multi wavelength & scan collection | yes |
| UV: 200 - 800 nm multi wavelength & scan collection | pack-UVextended |
| Spectral view and purity confirmation | yes |
| iELSD Detection (pack) | pack-iELSD |
| Injection | |
| 4 port electrical valve | no |
| 6 port electrical valve with loop | no |
| 6 port + 10 port electrical valves with loop | yes |
| Injection mode: liquid - dry-load | yes |
| Column Selection Valve | |
| 6 port electrical valve | pack-Multi |
| System Optimisation | |
| Tubing after pump | 1/8" x 1.6 mm ID |
| Flow cell: optical length/volume | 0.3 mm/40 µL |
| Column Holder | |
| Integrated | yes |
| Pre-column holder | yes |
| Fraction Collector | |
| Reglular collector | 3 racks Gen5 132 tubes 18 x 150 mm |
| Unit Control | |
| Touch screen 15" | yes |
| USB | 8 |
| RJ45 | yes |
| Safety | |
| Leak detection (pump, FC, iELSD, holders) | yes |
| Solvent tray with drainage system | yes |
| Collector with drainage system | yes |
| Solvent and waste level monitoring | yes |
| RFID | yes |
| Fume enclosure | yes |
| Size | Width: 40 cm Depth: 51 cm Height: 75 cm |