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HPLC Troubleshooting

We regularly get enquiries about problems in the lab that require troubleshooting. It can be really frustrating when trying to complete analyses and your instruments just won’t let you. That’s why we made note of the most common problems our customers encountered and turned them into helpful, technical articles.

Take a look and find some tips that will help you get your instruments back online and avoid extended downtime.

  1. Solving Practical HPLC Problems with Basic Theory

    Back to School – Solving Practical HPLC Problems with Basic Theory

    06 Jul 2021

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  2. Reducing non-specific protein binding in HPLC

    Reducing non-specific protein binding in HPLC

    20 Aug 2020

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  3. HPLC Diagnostic Skills III – Systematic Investigation of Selectivity Changes

    HPLC Diagnostic Skills III – Systematic Investigation of Selectivity Changes

    11 Feb 2020

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  4. HPLC Diagnostic Skills II - Tailing Peaks

    HPLC Diagnostic Skills II - Tailing Peaks

    19 Nov 2019

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  5. HPLC Troubleshooting Filtration

    HPLC Troubleshooting Filtration

    20 May 2019

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  6. HPLC Troubleshooting

    HPLC Troubleshooting

    10 May 2019

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  7. Reduce Instrument Downtime

    Reduce Instrument Downtime

    23 Apr 2019

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  8. HPLC Diagnostic Skills Vol I – Noisy Baselines

    HPLC Diagnostic Skills Vol I – Noisy Baselines

    04 Feb 2019

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  9. Troubleshooting HPLC Separation Issues - Are checklists only for pilots?

    Troubleshooting HPLC Separation Issues - Are checklists only for pilots?

    02 Nov 2017

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  10. Solid Phase Extraction Mistakes

    Solid Phase Extraction Mistakes

    03 Oct 2017

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  11. Polar analyte retention and phase collapse

    Polar analyte retention and phase collapse

    03 Oct 2017

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  12. Retention Time Variability in HPLC

    Retention Time Variability in HPLC

    03 Oct 2017

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