DISSOLUTION TRAINING COURSE
This training course provides a comprehensive overview of the entire dissolution testing process. It covers basic theory behind dissolution, look at the use of type 1 and type 2 apparatus, including calibration, calculation and evaluation of results and method development considerations.
This not only provides a good introduction to those new to dissolution but also provides substantial information to labs looking to develop their own methods or improve existing practice—an invaluable insight into dissolution testing.
This course is for analysts at many levels – for those new to dissolution testing who require a good foundation in the subject, more experienced analysts who need greater understanding to improve troubleshooting or labs needing to develop or optimise dissolution methods.
DISSOLUTION COURSE DETAILS
- Introduction – the human gastrointestinal tract and solid dose formulations
- Type 1 and Type 2 Dissolution apparatus
- Dissolution media
- Sampling
- System calibration and performance verification
- Calculation of results
- Method development
We offer flexible delivery options for this instructor-led course:
- On-site: one day at your lab or a location of your choice.
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Online: two half days.
View our online training calendar for upcoming dates.
Basic knowledge of chemistry is advantageous. Previous experience using dissolution equipment will be beneficial.
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Basics of Dissolution Testing
- Overview of the human GI tract
- Conventional oral solid dose formulations
- Apparatus 1 and 2 methods
- Typical system setup
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Dissolution Media
- Role of the media
- Common additives
- Deaeration
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Sampling Methods
- Manual and automated sampling
- Filtration
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Calculation of Results
- Q and instant release
- Mass and volume correction
- Common causes of result failures
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Equipment Verification
- Enhanced mechanical calibration
- Single and two-stage performance verification testing
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Method Development
- The development process
- Key method parameters
- Setting limits
