Advion-Interchim puriFlash 5.400-UV

The puriFlash 5.400-UV is a high-performance purification platform designed for advanced method development and preparative HPLC applications. This system supports seamless transition from analytical-scale evaluation on 7.8 mm internal diameter columns to large-scale purification on preparative HPLC columns, all within a single instrument. It is particularly suited to laboratories handling rare, high-value compounds where resolution, recovery, and reproducibility are critical.

With a maximum operating pressure of 400 bar, the 5.400-UV is compatible with sub-2 µm particle columns, enabling ultra-high resolution separations and superior peak definition. This capability ensures maximum separating power for challenging purifications, including those involving closely related compounds or trace-level targets.

The integrated mobile phase heating system maintains solvent temperature independently of ambient conditions, improving run-to-run reproducibility and peak sharpness. To protect sample integrity and system components, solvent level detectors issue alerts before reservoirs run dry, helping to prevent air introduction into the column flow path.

The system incorporates RFID recognition to enhance operational safety and reduces setup errors during method development or batch purification. Control and monitoring are managed via the intuitive ClearPeak interface and Genius software, displayed on a large 15″ touchscreen. Remote access capability further increases convenience, allowing users to track purification progress from any location.

Compact in design yet engineered for demanding applications, the puriFlash 5.400-UV offers a flexible and efficient solution for researchers and process chemists seeking precise, scalable purification with integrated safety and method control features.